Mutants: Genesis Tier List: Which Genes Reign Supreme?

Mutants: Genesis, set to launch on May 20, 2025, is an exciting strategic card battler where you take on the role of a Psycog. This article provides a detailed tier list for each gene, helping you understand which cards to prioritize in your deck-building strategy and dominate the battlefield.

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What is a Tier List?

For those new to the concept, a tier list is a ranking system that categorizes different elements of a game based on their strength, versatility, and effectiveness. In the context of Mutants: Genesis, it evaluates the various genes available to players. These genes determine the unique abilities and playstyles of the mutants you control. Understanding which genes are currently dominant can significantly impact your deck-building strategies and overall success in both PvE and PvP modes.

The Genes of Mutants: Genesis

Mutants: Genesis features six distinct genes, each offering a unique approach to gameplay:

• Blades: Known for their aggressive, brute strength and high damage output in close combat.
• Zoo: Focuses on overwhelming opponents with sheer numbers and diverse mutant creatures.
• Tech: Relies on advanced technology and strategic manipulation of the battlefield.
• Space: Brings cosmic elements and powerful, otherworldly abilities to the table.
• Mystic: Utilizes mystical forces, magic, and psychic powers for a more esoteric playstyle.
• Necro: Centers around death, decay, and the undead, with abilities that thrive in darker, more macabre scenarios.

The Six Genes of Mutants: Genesis & Their Tier Rankings

Below is a pre-launch tier list for each gene, including standout cards and strategic insights. Classes are ranked from S-Tier (meta-defining) to C-Tier (niche or situational), with notes on playstyle and key cards. Remember this tier list is compiled from pre-launch player experiences and is for reference only. We will further revise and improve it after the game launches on May 20.

S-Tier: Meta Dominators

Zoo Gene

• Playstyle: Swarm tactics, rapid unit deployment, and resource generation.
• Why It's Strong: Community feedback highlights Zoo's early-game aggression and low deck complexity. Cards like Leviathan (Advanced) can flood the board with area damage, while the Darwin (Heroic) passive summons evolved units over time.
• Key Cards:
  • Darwin (Heroic): Massive health + evolve mechanic to dominate late game.
  • Leviathan (Advanced): AoE damage + tanky stats to control the board.
  • Sgt. Pandamonium (Advanced): Resource generation for consistent combos.

Blades Gene

• Playstyle: High-damage melee units, frontline dominance, and taunt mechanics.
• Why It's Strong: Ideal for aggressive players. Cards like Spartac (Heroic) can soak damage with taunt, while Nordic Knightmare (Advanced) deals massive burst damage.
• Key Cards:
  • Spartac (Heroic): Taunt + massive stats to protect your backline.
  • Nordic Knightmare (Advanced): High attack/defense for mid-game control.
  • Valkyrie (Advanced): Heal + attack versatility for sustain.

A-Tier: Strong Contenders

Tech Gene

• Playstyle: Gadget-focused, resource manipulation, and defensive shields.
• Why It's Solid: Tech thrives on synergy, using cards like Goliath (Heroic) to deploy game-changing devices. Gargantua (Advanced) with shield generation can stall opponents.
• Key Cards:
  • Goliath (Heroic): Deploy tech devices to disrupt late-game strategies.
  • Gargantua (Advanced): Shield+high HP for unkillable frontlines.
  • R0B-H4N Sentinel (Advanced): Resource generation for consistent tech plays.

Necro Gene

• Playstyle: Undead resurrections, fear effects, and attrition warfare.
• Why It's Viable: The Forgotten One (Heroic) can revive fallen units, creating endless waves. Humongous (Advanced) uses fear to lock down enemies.
• Key Cards:
  • The Forgotten One (Heroic): Resurrect mutants to overwhelm opponents.
  • Humongous (Advanced): Fear + high stats to disrupt enemy positioning.
  • S-K-Venger (Advanced): Resource generation for undead combos.

B-Tier: Situational but Strategic

Space Gene

• Playstyle: Cosmic abilities, long-range attacks, and spatial manipulation.
• Challenges: Relies on niche cards like Zeus (Heroic), which requires setup (e.g., 3 Expandamonium for squad buffs). Early units like Squad cards are weak without synergies.
• Key Cards:
  • Zeus (Heroic): AoE lightning strikes for late-game board clears.
  • Selendis (Advanced): Spatial manipulation to disrupt enemy formations.
  • Humongous (Advanced): High HP/attack for stall tactics.

Mystic Gene

• Playstyle: Magic, psychic heals, and delayed spell combos.
• Challenges: Slow start; requires specific cards like Geomega (Heroic) to generate game-winning spells. Vulnerable to aggro decks.
• Key Cards:
  • Geomega (Heroic): Massive stats + spell generation for late-game dominance.
  • Mephisto (Advanced): DoT (damage over time) + disruption for control decks.
  • Valkyrie (Advanced): Heal support to keep key units alive.

C-Tier: High Risk, Low Reward (For Now)

No genes are fully "bad," but some require extreme niche strategies or unconfirmed synergies. For example, Space and Mystic may fall here pre-launch due to their reliance on rare cards or complex combos. Monitor post-launch updates for buffs!

People Also Ask

Q1: When is Mutants: Genesis being released?

A1: Mutants: Genesis is set to launch on May 20, 2025.

Q2: How can I play Mutants: Genesis on PC & Mac？

A2: You can play Mutants: Genesis on PC & Mac with MuMuPlayer which support multi-instance, and offer smooth keyboard and mouse operation.

Q3: How can I obtain cards in Mutants: Genesis?

A3: In Mutants: Genesis, you can acquire cards through various methods such as playing missions, completing challenges, earning rewards, and possibly through in-game purchases. The game offers over 200 collectible cards for you to build and customize your deck.

Q4: What are the different genes available in Mutants: Genesis?

A4: Mutants: Genesis features six distinct genes: Blades, Zoo, Tech, Space, Mystic, and Necro. Each gene offers a unique playstyle and set of abilities, allowing you to choose the one that best suits your strategic preferences.

MuMuPlayer – The Perfect Companion for Mutants: Genesis！

For the ultimate gaming experience, we suggest you download Mutants: Genesis on MuMuPlayer. This emulator offers several advantages:

• Smooth Gaming Experience: Experience Mutants: Genesis with minimal lag and stunning graphics.
• Smart Controls: Customize your keyboard and mouse settings for precise control.
• Multi-Tasking: Run multiple apps simultaneously without affecting performance.

Mastering the tier list for each gene in Mutants: Genesis is key to building powerful decks and achieving victory. Whether you're drawn to the aggressive strategies of Blades, the overwhelming numbers of Zoo, the technological prowess of Tech, the cosmic power of Space, the mystical forces of Mystic, or the dark allure of Necro, this tier list will guide you to strategically select and combine cards. Experiment with different playstyles and climb the ranks to become the ultimate Psycog when the game launches on May 20, 2025.